Exacerbation of Delayed Cell Injury After Transient Global Ischemia in Mutant Mice With CuZn Superoxide Dismutase Deficiency
نویسندگان
چکیده
منابع مشابه
Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency.
BACKGROUND AND PURPOSE We have demonstrated that copper-zinc superoxide dismutase (CuZn-SOD), a cytosolic isoenzyme of SODs, has a protective role in the pathogenesis of superoxide radical-mediated brain injury. Using mice bearing a disruption of the CuZn-SOD gene (Sod1), the present study was designed to clarify the role of superoxide anion in the pathogenesis of selective vulnerability after ...
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ژورنال
عنوان ژورنال: Stroke
سال: 1999
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.30.9.1962